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. 2020 Jul 28;9(15):e015566. doi: 10.1161/JAHA.119.015566

Table 4.

Univariate and Multivariate Analysis for Predictor of Postoperative AKI

Variables Univariate Analysis Model 1 Model 2
Multivariate Analysis Multivariate Analysis
OR (95% CI) P Value Adjusted OR (95% CI) P Value Adjusted OR (95% CI) P Value
Diabetes mellitus 2.5 (1.1–5.9) 0.030 2.4 (0.9–6.6) 0.08 2.5 (0.9–6.7) 0.06
Preoperative hemoglobin ≤11.6 g/dL 13.4 (3.9–46) <0.001 7.6 (2.0–32.3) 0.004 8.2 (2.1–34.3) 0.002
RBC transfusions during CPB ≥2 U 5.2 (1.9–13.7) <0.001 3.3 (1.0–11.1) 0.041 3.2 (1.0–10.8) 0.048
Nadir hemoglobin ≤7.4 g/dL 3.0 (1.3–7.0) 0.009 1.4 (0.4–5.3) 0.58 1.0 (0.3–3.9) 0.99
Nadir DO2 ≤265 mL/min per m2 3.0 (1.2–7.4) 0.012 1.7 (0.4–7.7) 0.48 1.4 (0.3–5.3) 0.65
Largest AUC below the DO2300 ≥880 5.4 (2.1–13.7) <0.001 4.9 (1.2–21.5) 0.022
Cumulative AUC below the DO2300 ≥1555 3.3 (1.4–7.8) 0.006 1.0 (0.3–4.3) 0.95

AKI indicates acute kidney injury; AUC, area under the curve; DO2, oxygen delivery; OR, odds ratio; and RBC, red blood cell.