Table 2.
Changes in Markers of Decongestion From Admission to Discharge and Clinical Outcomes by Obesity Category in Hospitalized HFpEF
| Obesity Category | P Value | |||
|---|---|---|---|---|
| Nonobese | Obese | Severely Obese | ||
| Markers of decongestion | ||||
| Percent change in absolute NT‐proBNP from admission to discharge | −46.9 (−57.8 to −37.4) | −40.4 (−74.3 to −12.0) | −64.8 (−85.4 to −38.9) | 0.025 |
| Weight change at discharge, kg | −5.3 (−7.0 to −2.6) | −3.2 (−6.6 to −1.5) | −2.8 (−7.3 to −1.0) | 0.310 |
| Net diuresis at discharge, mL | −7140.0 (−8653.0 to −3155.0) | −5418.0 (−8397.0 to −2522.0) | −6392.0(−10,662.0 to −3928.0) | 0.490 |
| 6MWT at discharge, m | 54.7 (29.3 to 142.6) | 121.9 (50.0 to 205.7) | 80.8 (30.5 to 166.7) | 0.750 |
| Clinical outcomes | ||||
| Development of WRF at 72 h | 2 (12) | 7 (27) | 10 (22) | 0.490 |
| Hospital length of stay, d | 7 (5–8) | 7 (5–10) | 7 (4–10) | 0.840 |
| All‐cause 30‐d readmission, No. (%) | 5 (29) | 4 (16) | 13 (28) | 0.470 |
| 1‐y Survival, No. (%) | 10 (63) | 19 (76) | 42 (95) | 0.005 |
Values are expressed as median (interquartile range) unless otherwise indicated. 6MWT indicates 6‐minute walk test; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; and WRF, worsening renal function.