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. 2021 Jan 7;16:9. doi: 10.1186/s13012-020-01078-9

Table 2.

Trial outcomes

Type Outcome Data source Definition When outcome is analyzed
Primary Reduction in inappropriate prescribing EHR Composite of (1) discontinuation of high-risk medications or (2) ordering a gradual dose taper End of stages 1 and 2
Secondary Quantity of prescribing EHR Number of milligram equivalents of high-risk medications prescribed to patients End of stage 2
Tertiary Quantity of medication dispensed Administrative claims Number of milligram equivalents of high-risk medications filled by patients End of stage 2
Adverse events Administrative claims Occurrence of clinically significant adverse drug events, such as all-cause hospitalizations, falls, and fractures End of stage 2