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. 2021 Jan 7;18:4. doi: 10.1186/s12014-020-09309-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — The total number of spectra for each protein was compared between biospecimens. Scatter plots of the total number of spectra identified for the proteins identified in all three biospecimens were created in Scaffold. Due to the large number of spectra from albumin identified in the Pap test fluid and cervical swab, this protein was omitted from the graphs. Comparison of the spectral counts for the proteins identified in: a tumor tissue extract and Pap test fluid, b tumor tissue extract and cervical swab, and c Pap test fluid and cervical swab. The Pap test fluid and swab samples were more similar to each other than to the tumor tissue extract. Red circle indicates serum proteins with similar spectral counts in the Pap test fluid and cervical swab. CYK4, cytokeratin-4; CYK13, cytokeratin-13