Table 2.
Characteristics of Hospitalized Patients With Acute HFpEF From the ARIC Community Surveillance Study by Sex and Race
| Women (n=5834) | Men (n=3153) | P Value | White Participants (n=6886) | Black Participants (n=2101) | P Value | |
|---|---|---|---|---|---|---|
| Age (mean), y | 78.1 (10.1) | 75.6 (10.8) | <0.001 | 78.9 (9.3) | 71.9 (12.2) | <0.001 |
| Men, % | … | … | … | 35.3 | 34.4 | 0.38 |
| Black participants, % | 23.6 | 22.9 | 0.38 | … | … | … |
| Admission to teaching hospital, % | 33.1 | 36.6 | 0.01 | 35.7 | 29.8 | 0.01 |
| History of HF hospitalization, % | 26.2 | 23.8 | 0.26 | 22.0 | 36.4 | <0.001 |
| Hypertension, % | 90.0 | 86.3 | 0.02 | 87.4 | 92.8 | 0.001 |
| Diabetes mellitus, % | 47.8 | 46.2 | 0.50 | 42.1 | 64.1 | <0.001 |
| Atrial fibrillation/flutter, % | 39.5 | 41.1 | 0.51 | 44.8 | 24.5 | <0.001 |
| Coronary artery disease, % | 40.4 | 51.8 | <0.001 | 45.9 | 39.3 | 0.01 |
| Pulmonary hypertension, % | 22.8 | 16.7 | 0.003 | 20.4 | 21.7 | 0.52 |
| Sleep apnea, % | 12.6 | 21.0 | <0.001 | 14.9 | 17.7 | 0.13 |
| COPD, % | 38.0 | 38.0 | 0.98 | 38.6 | 36.2 | 0.35 |
| End‐stage renal disease, % | 4.3 | 6.9 | <0.001 | 3.6 | 10.3 | <0.001 |
| Heart rate, beats per min | 87.5 (23.3) | 84.7 (24.0) | 0.02 | 87.1 (22.8) | 84.7 (24.9) | 0.04 |
| SBP, mm Hg | 146.7 (32.0) | 146.7 (32.7) | 0.99 | 144.4 (29.1) | 154.1 (41.4) | <0.001 |
| BMI, kg/m2 | 31.6 (11.7) | 30.6 (8.6) | 0.03 | 30.3 (9.5) | 34.6 (14.4) | <0.001 |
| Sodium (worst), mmol/L | 135.8 (4.6) | 136.5 (4.4) | 0.002 | 135.9 (4.3) | 136.5 (5.0) | 0.02 |
| eGFR (worst), mL/min per 1.73 m2 | 38.8 (20.7) | 42.3 (24.9) | 0.002 | 40.2 (19.4) | 39.5 (31.7) | 0.56 |
| BNP (worst), pg/mL | 981.4 (1970.5) | 857.5 (1026.5) | 0.15 | 938.0 (1731.0) | 932.7 (1247.7) | 0.95 |
| NT‐proBNP (worst), pg/mL | 8055.4 (14615.8) | 8177.3 (12412.9) | 0.94 | 6726.6 (8139.2) | 9843.4 (19357.5) | 0.11 |
| Hemoglobin (last), g/dL | 11.0 (1.7) | 11.5 (2.1) | <0.001 | 11.3 (1.7) | 10.8 (2.3) | <0.001 |
Data are reported as number (percentage), mean (SD), or median [interquartile interval]. ARIC indicates Atherosclerosis Risk in Communities; BMI, body mass index; BNP, B‐type natriuretic peptide; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; HF, heart failure; HFpEF, heart failure with preserved ejection fraction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; and SBP, systolic blood pressure.