Table 5.
Adjusted HRs of SCD by C‐IMTs (Above Versus Below Median) Across Demographic and Clinical Subgroups in CHS
| Variable | Maximum C‐IMT | Maximum CCA‐IMT |
|---|---|---|
| Age | 0.294 | 0.217 |
| Below median | 1.70 (1.18–2.46) | 1.13 (0.80–1.60) |
| Above median | 1.31 (0.96–1.81) | 1.51 (1.09–2.10) |
| Sex | 0.709 | 0.966 |
| Women | 1.38 (1.00–1.90) | 1.30 (0.94–1.79) |
| Men | 1.51 (1.06–2.17) | 1.28 (0.90–1.83) |
| Race | 0.397 | 0.655 |
| White | 1.77 (1.03–3.05) | 1.46 (0.810–2.64) |
| Black | 1.37 (1.05–1.79) | 1.26 (0.96–1.64) |
| CHD | 0.016 | 0.088 |
| No | 0.96 (0.64–1.43) | 0.98 (0.66–1.45) |
| Yes | 1.75 (1.30–2.35) | 1.49 (1.11–2.02) |
| HF | 0.966 | 0.612 |
| No | 1.41 (0.59–3.36) | 1.07 (0.50–2.30) |
| Yes | 1.44 (1.11–1.85) | 1.31 (1.02–1.70) |
| Diabetes mellitus | 0.271 | 0.174 |
| No | 1.81 (1.12–2.94) | 1.74 (1.05–2.90) |
| Yes | 1.33 (1.01–1.76) | 1.17 (0.89–1.55) |
| Hypertension | 0.457 | 0.394 |
| No | 1.54 (1.14–2.08) | 1.39 (1.03–1.88) |
| Yes | 1.28 (0.86, 1.90) | 1.12 (0.76, 1.68) |
| Obesity (BMI ≥ 30 kg/m2) | 0.678 | 0.838 |
| No | 1.30 (0.77–2.20) | 1.22 (0.71–2.10) |
| Yes | 1.48 (1.12–1.94) | 1.30 (0.99–1.70) |
Age: median=72 years in CHS.
BMI indicates body mass index; CCA‐IMT, common carotid artery intima‐media thickness; CHD, coronary heart disease; CHS, Cardiovascular Health Study; C‐IMT, carotid intima‐media thickness; HF, heart failure; HR, hazard ratio; and SCD, sudden cardiac death.