Table 2.
Relative Risk of All‐Cause and Cardiovascular Death During Follow‐Up Associated With CKD
| Univariate Analysis HR (95% CI) | P Value | Multivariable Analysis* HR (95% CI) | P Value | |
|---|---|---|---|---|
| All cause death | ||||
| No CKD | Reference | Reference | ||
| Mild CKD | 1.44 (1.27–1.65) | <0.001 | 1.04 (0.85–1.29) | 0.56 |
| Moderate CKD | 1.95 (1.67–2.26) | <0.001 | 1.36 (1.08–1.71) | 0.009 |
| Severe CKD | 3.18 (2.65–3.81) | <0.001 | 2.16 (1.76–2.79) | <0.001 |
| Cardiovascular death | ||||
| No CKD | Reference | Reference | ||
| Mild CKD | 1.43 (1.22–1.68) | <0.001 | 1.08 (0.82–1.43) | 0.60 |
| Moderate CKD | 2.03 (1.69–2.43) | <0.001 | 1.39 (1.03–1.88) | 0.031 |
| Severe CKD | 2.87 (2.29–3.61) | <0.001 | 1.69 (1.18–2.41) | 0.004 |
Results of cox analyses. CI indicates confidence interval; CKD, chronic kidney disease; and HR, hazard ratio.
After adjustment for age, sex, body surface area, Charlson comorbidity index, New York Heart Association class, history of hypertension, coronary artery disease, atrial fibrillation, left ventricular ejection fraction, Vmax, and aortic valve replacement treated as a time‐dependent variable.