Table 1.
The values of medians and ranges of concentrations (pg/ml) for the studied immunological parameters with division to subgroups
| Immunological parameters | Whole group (n = 163) | Control group (n = 48) | p-value | Severe infection (n = 75) | Without infection (n = 88) | p-value | Survival (n = 113) | Decease (n = 50) | p-value |
|---|---|---|---|---|---|---|---|---|---|
| IL-6 | 47.91 range: 0.04-960.49 | 1.50 range: 0.00-613.05 | 0.0000 | 47.80 range: 1.43-423.16 | 49.37 range: 0.04-960.49 | > 0.05 | 46.61 range: 0.04-619.75 | 53.76 range: 8.40-960.49 | 0.0016 |
| sTNFR1 | 8,992.60 range: 21.31-47,921.30 | 200.32 range: 27.11-4,864.50 | 0.0000 | 20,833.70 range: 251.78-47,921.30 | 815.63 range: 21.310-46,794.50 | 0.0000 | 10,353.00 range: 21.31-45,572.80 | 25,665.65 range: 9,651.30-47,921.30 | 0.0039 |
| TNF-α | 25.41 range: 1.99-491.85 | 13.29 range: 0.36-321.96 | 0.0000 | 27.18 range: 2.62-194.98 | 24.38 range: 2.00-491.85 | > 0.05 | 24.69 range: 2.00-491.85 | 27.78 range: 3.54-266.10 | > 0.05 |
| MyD88 | 0.00 range: 0.00-14,712.00 | 476.00 range: 0.00-19,168.00 | 0.0000 | 0.00 range: 0.00-13,536.00 | 0.00 range: 0.00-14,712.00 | > 0.05 | 0.00 range: 0.00-14,712.00 | 0.00 range: 0.00-11,372.00 | > 0.05 |
| TNFAIP3/A20 | 1.35 range: 0.14-20.98 | 5.20 range: 0.06-20.50 | 0.0007 | 1.14 range: 0.23-15.44 | 1.92 range: 0.14-20.98 | > 0.05 | 3.14 range: 0.00-20.98 | 5.51 range: 0.00-16.94 | > 0.05 |
| IL-1Ra | 616.57 range: 104.48-4,200.00 | 387.42 range: 9.74-2,665.70 | 0.0117 | 900.38 range: 135.54-4,200.00 | 589.24 range: 104.48-3,999.36 | > 0.05 | 589.24 range: 104.48-4,145.01 | 2,439.78 range: 135.54-4,200.00 | > 0.05 |
| IL-10 | 0.00 range: 0.00-918.69 | 0.00 range: 0.00-21.77 | > 0.05 | 0.00 range: 0.00-918.69 | 0.00 range: 0.00-339.41 | 0.0081 | 0.00 range: 0.00-918.69 | 7.50 range: 0.00-339.41 | 0.0217 |
| sTLR4 | 0.47 range: 0.45-1.10 | 0.46 range: 0.45-0.55 | 0.0000 | 0.46 range: 0.45-1.10 | 0.48 range: 0.46-0.55 | 0.0002 | 0.47 range: 0.45-1.10 | 0.46 range: 0.45-0.50 | > 0.05 |
| HSP70 | 0.10 range: 0.00-11.81 | 0.22 range: 0.00-2.68 | > 0.05 | 0.09 range: 0.03-1.29 | 0.10 range: 0.00-11.81 | > 0.05 | 0.08 range: 0.00-2.13 | 0.25 range: 0.00-1.81 | 0.0165 |
| HMGB1 | 0.00 range: 0.00-3.65 | 0.00 range: 0.00-3.88 | > 0.05 | 0.00 range: 0.00-0.00 | 0.00 range: 0.00-3.65 | > 0.05 | 0.00 range: 0.00-3.65 | 0.00 range: 0.00-0.97 | > 0.05 |