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Activation of AKT reverses the effect of ACTL6A knockdown on cell migration. A wound-healing assay was used to demonstrate the restorative effect of the AKT agonist SC79 on the migration of (A) U251 and (B) T98G cells following ACTL6A knockdown. sh, short hairpin; ACTL6A, actin-like 6A; Ctrl, control. The areas of the wounds were assessed at 5x magnification. *P<0.05, **P<0.01 vs. shCtrl.
