Fig. 8.
Right ventricle/left ventricle (RV/LV) free wall thickness ratio at PND14 in C57BL/6J wild-type mice exposed to LPS and hyperoxia during the saccular phase of lung development. C57BL/6J wild-type mice were exposed to either 21% O2 (normoxia) or 70% O2 (hyperoxia) during postnatal days (PNDs) 1–5 and injected intraperitoneally with 6 (L6) mg/kg of LPS or the vehicle (PBS) on PNDs 3–5. The mice were euthanized on PND 14 for heart morphometry. The RV/LV free wall thickness ratio was estimated from hematoxylin-and-eosin-stained heart sections. Values are expressed as means ± SD (n = 4–6 mice/group).