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. 2020 Oct 26;319(6):F1073–F1080. doi: 10.1152/ajprenal.00354.2020

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Published by the American Physiological Society

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Fig. 2. — Compound C blocks p53 phosphorylation, Bax induction, and caspase 3 activation induced by cisplatin in tubular epithelial cells. A: representative Western blots showing phosphorylated (p-)p53, p53, Bax, cleaved caspase 3, and GAPDH in tubular epithelial cells. B: quantitative analysis of p-p53/p53 in tubular epithelial cells. **P < 0.01. C: quantitative analysis of Bax expression in tubular epithelial cells. **P < 0.01. D: quantitative analysis of cleaved caspase 3 in tubular epithelial cells. **P < 0.01.