Fig. 1.

TMP195 administration protects against lipopolysaccharide (LPS)-induced acute kidney injury (AKI) in mice. A and B: after various treatments for 24 h, as indicated in materials and methods, blood was collected and serum creatinine and blood urea nitrogen (BUN) were measured. C: periodic acid-Schiff (PAS) staining of the kidneys (magnfication: ×200). D: morphological changes were scored based on the scale described in material and methods. Data are presented as means ± SE; n = 5. ***P < 0.001.