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. 2020 Oct 9;319(6):H1474–H1481. doi: 10.1152/ajpheart.00502.2020

Table 2.

Multiple linear regression analysis to estimate left ventricular end-diastolic and mean diastolic pressures

Model 1: Including LVEF
Model 2: Including LV Infarct Size
β 95% CI P β 95% CI P
Dependent variable: LV end-diastolic pressure
Intercept 26.44 16.38 to 36.51 <0.001 17.89 7.25 to 28.53 0.001
LVEF, per 5% −0.18 −1.04 to 0.68 0.68
Global longitudinal strain, % 0.50 0.06 to 0.93 0.026 0.37 0.02 to 0.72 0.037
Heart rate, per 10 beats/min −0.22 −0.96 to 0.52 0.55 −0.10 −0.82 to 0.63 0.79
LV end-systolic wall stress, per 10 dyn/mm2 0.23 −0.08 to 0.54 0.14 0.31 0.03 to 0.59 0.033
Interval between MI and measurements*
 2 wk 2.77 −0.84 to 6.37 0.13 2.98 −0.50 to 6.46 0.093
 4 wk −1.96 −4.74 to 0.82 0.16 −0.47 −3.45 to 2.51 0.75
LV infarct size, % of LV mass
 >20% 4.72 1.27 to 8.17 0.008
 Unavailable 2.38 −0.55 to 5.31 0.11
Dependent variable: LV mean diastolic pressure
Intercept 13.28 6.34 to 20.23 <0.001 9.98 2.41 to 17.56 0.010
LVEF, per 5% −0.07 −0.67 to 0.52 0.81
Global longitudinal strain, % 0.50 0.20 to 0.80 0.001 0.46 0.21 to 0.70 <0.001
Heart rate, per 10 beats/min 0.14 −0.37 to 0.65 0.59 0.21 −0.30 to 0.73 0.42
LV end-systolic wall stress, per 10 dyn/mm2 0.28 0.06 to 0.49 0.012 0.31 0.10 to 0.51 0.003
Interval between MI and measurements*
 2 wk 1.46 −1.03 to 3.95 0.25 1.59 −0.89 to 4.06 0.21
 4 wk −2.15 −4.07 to −0.23 0.028 −1.79 −3.91 to 0.33 0.097
LV infarct size, %LV mass
 >20% 1.47 −0.98 to 3.93 0.24
 Unavailable 0.99 −1.09 to 3.08 0.35

LV, left ventricular; LVEF, left ventricular ejection fraction; MI, myocardial infarction.

*

Reference interval is 1 wk after MI.

Reference LV infarct size is ≤20% of LV mass.