Fig. 9.

Left common carotid (LCC) and ascending aorta (ASC) circumferential stretch ratio (A and B) and circumferential stress (C and D) at the average systolic pressure for each group of male and female Eln^+/+ and Eln^+/− mice at 6, 12, and 24 mo of age. The letters in A–D, top, indicate independent variables and their interactions with P < 0.05 by three-way ANOVA. A, age; S, sex; G, genotype. *Significantly different between genotypes of the same age and sex by Tukey-Kramer post hoc test. Exact P values are given in Supplemental Table S1, and percent variation contributions are given in Supplemental Table S2. Independent data points with means ± SD are shown; n = 8–11 for each group.