Table 5. – Hazard Ratios for high Netrin-1 and IL-1β and all-cause mortality, cardiovascular mortality and fatal or new non-fatal MI in older (>60 years) females.

	All-cause mortality		Cardiovascular mortality		Fatal or new non-fatal MI
	HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)	p
	Netrin-1
Crude	2.15 (1.17 – 3.93)	0.013	2.31 (1.09 – 4.92)	0.029	2.25 (0.92 – 5.54)	0.075
Adjusted *	2.08 (1.04 – 4.16)	0.038	2.68 (1.06 – 6.74)	0.036	1.82 (0.65 – 5.07)	0.247
	IL-1β
Crude	1.57 (0.87 – 2.81)	0.127	2.23 (1.05 – 4.75)	0.036	2.27 (0.92 – 5.58)	0.073
Adjusted *	2.03 (1.06 – 3.89)	0.031	3.01 (1.26 – 7.17)	0.013	3.05 (1.12 – 8.32)	0.029

CI: confidence interval. HR: hazard ratio. IL-1β: Interleukin - 1beta. MI: myocardial infarction. * Adjusted for age, type of Acute Coronary Syndrome, diabetes, hypertension and dyslipidemia.