TABLE 3.

Diagnostic accuracy of nasal nitric oxide (nNO), transmission electron microscopy (TEM) and genetic evaluation for diagnosis of primary ciliary dyskinesia

	nNO <77 nL·min−1	nNO <30 nL·min−1	TEM	WES
All subjects, including unresolved diagnosis (n=57)	48	48	41	48
Sensitivity (95% CI)	100 (89.1–100)	93.8 (79.2–99.2)	62.2 (44.8–77.5)	94.4 (81.3–99.3)
Specificity (95% CI)	50.0 (21.1–78.9)	75.0 (42.8–94.5)	85.7 (57.2–98.2)	100 (73.5–100)
ROC area (95% CI)	0.75 (0.60–0.90)	0.84 (0.71–0.98)	0.74 (0.62–0.86)	0.97 (0.93–1.0)

WES: untargeted whole-exome sequencing; ROC: receiver operating characteristic.