Table 3.

Brachial artery hemodynamics during assessment of endothelium-dependent vasodilation

	Placebo		TUDCA
	Pre-I/R	Post-I/R	Pre-I/R	Post-I/R
Baseline diameter, cm	0.353 ± 0.062	0.362 ± 0.064	0.347 ± 0.055	0.350 ± 0.053
Peak diameter, cm	0.370 ± 0.062	0.373 ± 0.060	0.367 ± 0.054	0.365 ± 0.053
ΔDiameter, cm	0.017 ± 0.007	0.011 ± 0.009*	0.020 ± 0.008	0.015 ± 0.008*
Time to peak diameter, s	49 ± 34	48 ± 29	54 ± 40	62 ± 55
Shear rate AUC	42,267 ± 13,302	42,380 ± 14,990	48,773 ± 23,773	48,912 ± 21,547

Values are means ± SD. Shear rate AUC, shear rate area under the curve through peak diameter; TUDCA, tauroursodeoxycholic acid; I/R, ischemia-reperfusion.

^*P < 0.01 vs. pre-I/R.