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. 2020 Dec 22;22(1):37. doi: 10.3390/ijms22010037

Figure 4.

Figure 4

Mitochondrial reactive oxygen species (ROS) production. CDN1163 injections but not diet reduced the mitochondrial ROS production during state-1 (A) (without mitochondrial substrate) and in the presence of respiratory substrates (B) (glutamate/malate; G/M) in the gastrocnemius muscles of 26-month-old aged mice when compared to vehicle treated control group. Values are expressed as mean ± SEM; (n = 8–9 mice/group); one-way analysis of variance. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001.