a. The correlation of the SNPs in the CHRNA5-CHRNA3-CHRNB4 gene region.
b. The correlation of the SNPs in the CYP2A6 gene region.
The top half of the matrix represents the genetic correlation of each pairwise comparison of all outcomes. Blue represents a positive correlation. Red represents a negative correlation. The size of the colored squares as well as the depth of the color represents the strength of the genetic correlation. The bottom half of the matrix represents the numerical value of each respective genetic correlation. The diagonal is the correlation of SNPs within the same outcome.