AGEs	Advanced glycation end products
AgRP	Agouti-related protein
AD	Alzheimer’s disease
Aβ	Amyloid-β
Ang-1	Angiopoietin 1
ARC	Arcuate nucleus of the hypothalamus
Atg4B	Autophagy related gene 4B
Bcl-2	B-cell lymphoma 2
BDNF	Brain-derived neurotrophic factor
CNS	Central nervous system
CSVD	Cerebral small vessel disease
CART	Cocaine and amphetamine-related transcript
DM	Diabetes Mellitus
DCN	Diabetic corneal neuropathy
DPN	Diabetic peripheral neuropathy
Dicer	Endoribonuclease
DIO	Diet-induced obesity
DRG	Dorsal root ganglia
ECs	Endothelial cells
GAS5	Growth arrest-specific transcript 5
GFAP	Glial fibrillary acidic protein
GFP	Green fluorescent protein
HO-1	Heme oxygenase-1
HG	High glucose
hCMEC/D3	Human cerebral endothelial cell model
HD	Huntington’s Disease
IRS-1	Increased insulin receptor substrate 1
iPSC	Induced pluripotent stem cells
IRS-1	Insulin receptor substrate 1
IRAK1	Interleukin 1 Receptor Associated Kinase 1
IL-1β	Interleukin-1β
IL-2	Interleukin 2
IL-6	Interleukin 6
IP	Intraperitoneal
LARP7	La ribonucleoprotein domain family member 7
lncRNA	Long noncoding RNA,
MSC	Mesenchymal stromal cells,
MALAT1	Metastasis-associated lung adenocarcinoma transcript 1
miRs	MicroRNAs, miRNAs
LC3-II	Microtubule-associated protein 1 light chain 3
miRISC	MiRNA induced silencing complex
MCP-1	Monocyte chemotactic protein-1
NOX4	NADPH oxidase 4
NTC	Negative Treated Control
NPY	Neuropeptide Y
NEAT1	Nuclear paraspeckle assembly transcript 1
Nrf2	Nuclear factor erythroid 2-related factor 2
NF-κB	Nuclear factor kappa-light-chain-enhancer of activated B cells
PD	Parkinson’s Disease,
PTIP 1	Pax transactivation domain-interacting protein 1
p-NFkB	Phospho NFkB
PDE3A	Phosphodiesterase 3a
POMC	Pro-opiomelanocortin
PDCD4	Programmed cell death protein 4
Ago-2	Protein argonaute-2
qPCR	Quantitative real-time PCR
ROS	Reactive oxygen species
RAGE	Receptor for advanced glycation end
RGCs	Retinal ganglion cells
Sirt1	Silent mating type information regulation 2 homolog 1
Sox2OT	Sox2 overlapping transcript
STZ	Streptozocin
Tβ4	Thymosin beta 4
TRAF6	TNF Receptor Associated Factor 6
TLR4	Toll-like receptor 4
TRPM7	Transient receptor potential melastatin 7
TRAF6	Tumor necrosis factor (TNFR)-associated factor 6
TNF-α	Tumor necrosis factor α
T1DM	Type 1 Diabetes Mellitus
UTR	30 untranslated region
VCAM-1	Vascular cell adhesion molecule-1
VEGF	Vascular endothelial growth factor
YFP	Yellow fluorescent protein