Table 2.

The diagnostic accuracy of serum fibrosis markers for significant fibrosis.

	PPV	NPV	Sensitivity	Specificity
WFA+-M2BP ≥ 1.2 COI	43.5%	84.0%	71.4%	61.8%
FIB-4 ≥ 2.67	41.2%	77.4%	50.0%	70.6%
NAFLD fibrosis score ≥ 0.675	60.0%	74.4%	21.4%	94.1%
APRI ≥ 1.5	No subject met the criteria of APRI ≥ 1.5

PPV—positive predictive value; NPV—negative predictive value; WFA+-M2BP—Wisteria floribunda agglutinin-positive mac-2 binding protein; COI—cut-off index; NAFLD—nonalcoholic fatty liver disease; APRI—aspartate aminotransferase-to-platelet ratio index.