Table 3.
Factors associated with significant fibrosis.
| OR | 95% CI | p-Value | |
|---|---|---|---|
| Age (per 10 years) | 0.75 | 0.4–1.3 | 0.3 |
| Sex (female) | 0.71 | 0.2–2.6 | 0.6 |
| BMI, kg/m2 | 1.16 | 0.9–1.5 | 0.2 |
| Albumin < 4.1 g/dL * | 2.44 | 0.7–9.2 | 0.2 |
| AST > 38 IU/L * | 4.4e7 | 0.0–inf | 0.9 |
| ALT > 43 IU/L * | 2.54 | 0.2–43 | 0.5 |
| Gamma-glutamyl transpeptidase >80 IU/L for male and >40 IU/L for female * | 2.59 | 0.6–10 | 0.2 |
| Platelet counts < 160 (109/L) * | 1.54 | 0.4–5.9 | 0.5 |
| Presence of fatty liver | 0.79 | 0.2–2.9 | 0.7 |
| Presence of hypertension | 1.07 | 0.3–3.8 | 0.9 |
| Presence of diabetes mellitus | 2.82 | 0.5–16 | 0.2 |
| Presence of dyslipidemia | 1.30 | 0.3–5.3 | 0.7 |
| Presence of significant alcohol consumption | 4.13 | 0.8–21 | 0.1 |
| WFA+-M2BP ≥ 1.2 COI | 4.04 | 1.1–16 | 0.04 |
| FIB-4 ≥ 2.67 | 2.40 | 0.7–8.6 | 0.2 |
| NAFLD fibrosis score ≥ 0.675 | 4.36 | 0.6–29 | 0.1 |
Bold characters indicate factors with p value < 0.05. * The threshold was determined by the upper limit of normal. BMI—body mass index; AST—aspartate aminotransferase; ALT—alanine aminotransferase; WFA+-M2BP—Wisteria floribunda agglutinin-positive mac-2 binding protein; COI—cut-off index; OR—odds ratio; CI—confidence interval; NAFLD—nonalcoholic fatty liver disease. Data are shown as the mean ± standard deviation.