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. 2020 Dec 28;16(12):e1009152. doi: 10.1371/journal.ppat.1009152

Fig 1. Astroglial Cx43 aggravates PN meningitis.

Fig 1

a, symptoms of C57/BL6 mice proficient (aCx43FL/FL) or deficient (aCX43-/-) for astroglial Cx43 following intravenous PN challenge. b, c, box plots showing medians of CFU determination associated with brain (B) or blood (C) samples at the indicated post-infection time. Grey boxes: aCx43FL/FL mice; empty boxes: aCX43-/-mice. b, aCx43FL/FL: 3H, N = 4; 6H, N = 4, 13H, N = 5; 24H, N = 12. aCx43-/: 3H, N = 4; 6H, N = 4, 13H, N = 3; 24H, N = 12. c, aCx43FL/FL: 3H, N = 4; 6H, N = 4, 13H, N = 5; 24H, N = 9. aCx43-/- 3H, N = 4; 6H, N = 4, 13H, N = 3; 24H, N = 9. Wilcoxon test. **: p = 0.01; ****: p < 0.0001.