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. 2021 Jan 8;100(1):e24145. doi: 10.1097/MD.0000000000024145

Figure 1.

Figure 1

Temporal trends in IV rt-PA and EVT use for acute ischemic stroke. Each point indicates the monthly number of patients treated with EVT alone (open circles), EVT alone or combined with IV rt-PA (closed circles), IV rt-PA alone (open diamonds), or reperfusion therapy involving EVT and/or IV rt-PA (closed diamonds). The dashed lines and shaded areas represent the regression lines and 95% confidence intervals, respectively, for each group. The therapeutic time window was extended from 3.0 to 4.5 hours in September 2012 (vertical dashed line). Each year indicates the Japanese fiscal year from April to March.