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. 2020 Dec 23;26(1):36. doi: 10.3390/molecules26010036

Table 1.

CPP-PS and CPP-cargo-PS conjugates for PCI.

Conjugate Response After Photoirradiation 1O2 Quantum Yield PS at N or C Terminal References
Tat–Ce6
Ce6–Tat		 Enhanced delivery of toxin protein High
(0.62 and 0.69 for Ce6–Tat and Tat-Ce6, respectively, in CD3OD) 		N/C [43]
Tat–porphyrin
porphyrin–Tat		 Enhanced delivery of toxin protein - N/C [52]
Tat–TPP * Enhanced delivery of toxin protein High
(0.54 in CD3OD)		 C [61]
TatU1A–Alexa546
TatU1A–Alexa633
TatU1A–DY750
FHVU1A–Alexa546
TatSxl–Alexa546		 Cytosolic delivery of RNAs and photoinduced RNAi Very low
(0.028 and 0.043 for Alexa546 and Alexa633, respectively, in octanol)		 C [17,30,35,58]
TatBim–Alexa546 Cytosolic delivery of Bim peptide and photoinduced apoptosis - C [59]
Biotinylated TP10
+ streptavidin–Alexa633		 Cytosolic delivery of streptavidin–Alexa633 - N [32]

* 5,10,15,20-Tetraphenylporphine.