Table 4.

Univariate and multivariate odds ratios for sum negative Life Events.

	Cases (N = 664)		Controls (N = 203)		OR	95% CI		Adj. ORa	95% CI
	N	%	N	%
Stressful negative valence LEs
0 events	123	18.5	45	22.2
1 event	111	16.7	29	14.3	1.40	0.82	2.39	1.43	0.81	2.53
2 events	84	12.7	46	22.7	0.67	0.41	1.10	0.81	0.47	1.38
3 events	109	16.4	29	14.3	1.38	0.81	2.34	1.57	0.89	2.77
≥4 events	237	35.7	54	26.6	1.61	1.02	2.52	1.62	0.99	2.63
P trendb					0.042			0.049
Non-stressful negative valence LEs
0 events	526	79.2	161	79.3
1 event	46	6.9	18	8.9	0.78	0.44	1.39	0.77	0.42	1.42
2 events	30	4.5	13	6.4	0.71	0.36	1.39	0.58	0.28	1.19
3 events	21	3.2	6	3.0	1.07	0.43	2.70	0.80	0.31	2.10
≥4 events	41	6.2	5	2.5	2.51	0.98	6.46	2.04	0.77	5.41
P trendb					0.227			0.760

N: number of exposed; %: percent exposed.

^aAdjusted for reference age, age at first full term pregnancy, menopausal status, family history of breast cancer, HRT use, smoking history, education level, race/ethnicity and physical activity.

^bP trend computed by incorporating negative valence LE (NSLE) sum in the logistic regression model as a continuous variable.