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. 2020 Dec 23;10:615298. doi: 10.3389/fonc.2020.615298

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Copyright © 2020 Chahoud, Skelton, Spiess, Walko, Dhillon, Gage, Johnstone and Jain

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Squamous cell carcinoma with perinodal extension into fat (4X magnification). (B) Cross section through the CT portion of the PET/CT prior to the initiation of immunotherapy. The largest lymph node measures 5.6 x 4.3 cm transverse (arrows). (C) Noncontrast CT of the pelvis obtained approximately 1 month after initiation of immunotherapy reveals decreasing lesion size (arrowheads) now measuring 4.2 x 3.8 cm (arrowheads). Subsequent contrast enhanced CTs at 3 months (D) and 36 months (E) after initiation of immunotherapy show no evidence of residual nodal disease.