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. 2020 Dec 22;11:568805. doi: 10.3389/fmicb.2020.568805

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Copyright © 2020 Qiao, Wang, Zhang, Han, Feng and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The WNT/β-catenin signaling pathway in dendritic cells (DCs) was activated by BD3526 metabolites. The expression levels of IRF8, CD83, and CD74 (shown in A–C, respectively) in the BD3526 group and the NC group were analyzed using qRT-PCR (**P < 0.01, *P < 0.05, mean ± SEM). (D,E) The expression and distribution of c-myc and BCL9, respectively, in DCs. (F) Quantitative analysis of the anti-inflammatory factor interleukin (IL)-10 in the BD3526 and NC groups (*P < 0.05, mean ± SEM). (G) Quantitative analysis of the chemokine transforming growth factor (TGF)-β in the BD3526 and NC groups (**P < 0.01, mean ± SEM).