Figure 1.

Summary of current applications and advances of DIA mass spectrometry in neuroproteomics. Several studies (purple) have successfully applied DIA mass spectrometry for the quantification of the brain proteome, including the analysis of developmental and pathological protein changes. Recent advances in DIA (green) have allowed the reliable quantification of a higher number of proteins in less time by the development of acquisition methods and improved references databases, either empirical, predicted, or hybrid libraries.