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Representative left ventricular (LV) hemodynamic changes measured by implantable pressure-telemetry during an acute swim bout in mice. During a 90 min swim bout, LV diastolic filling pressures (red) increase rapidly from a baseline of ∼10 mmHg to ∼45 mmHg within the first 10 min. Thereafter, the pressure falls to ∼20 mmHg, only to rise steadily to ∼40–45 mmHg by the end of the 90 min swim.
