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. 2020 Dec 18;12:601965. doi: 10.3389/fnagi.2020.601965

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Copyright © 2020 Liu, Chen, Chen and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hierarchical clustering dendrogram and heat map. (A) Hierarchical clustering based on the expression value of circularRNA (circRNA) shows a distinguishable gene expression profile among the samples. The green strip indicates low relative expression, and the red strip indicates high relative expression. (B) Box plots show the distribution of circRNAs in the two groups, which were similar after normalization. (C) Scatter plot indicates a change of >1.5-fold in circRNA levels between the two groups.