Skip to main content
. 2020 Dec 18;12:601965. doi: 10.3389/fnagi.2020.601965

Figure 2.

Figure 2

Deregulated hsa_circ_0003391 in the peripheral blood of patients with AD compared to patients with other types of dementia. The expression of hsa_circ_0003391 from the plasma of 30 patients with Alzheimer's disease (AD) and 30 age-matched controls by quantitative real-time PCR (RT-Qpcr) (A–D). The receiver operating characteristic (ROC) curve analysis of hsa_circ_0003391 in the AD group is shown and the area under the curve (AUC) values are provided on the graphs (E–G). RT-qPCR validation assay of the expression levels of hsa_circ_0003391 in the peripheral blood cells of 50 patients with AD, 50 age-matched controls, 20 patients with dementia with Lewy bodies (DLB), and 40 patients with vascular dementia (VD) (H). The ROC curve analysis of the expression of hsa_circ_0003391 in AD blood cells is shown (I). Data were analyzed using Student's t-test and a one-way ANOVA. **p < 0.01, ***p < 0.001, ****p < 0.0001.