Table 3.
The top 10 upregulated and downregulated circRNAs detected by microarray analysis in the AD group.
| Circ ID | Gene Symbol | Location | Type | FC (abs) | P-value |
|---|---|---|---|---|---|
| Downregulated circRNAs | |||||
| hsa_circ_0050212 | RFXANK | chr19 | Exonic | 4.7437 | 0.0191 |
| hsa_circ_0049586 | TNPO2 | chr19 | Exonic | 4.6861 | 0.0201 |
| hsa_circ_0003859 | LTBP4 | chr19 | Exonic | 4.5214 | 0.0461 |
| hsa_circ_0066336 | FLNB | chr3 | Exonic | 4.3493 | 0.0167 |
| hsa_circ_0066331 | FLNB | chr3 | Exonic | 4.1721 | 0.0218 |
| hsa_circ_0003391 | UBASH3B | chr11 | Exonic | 4.0117 | 0.0215 |
| hsa_circ_0050745 | CAPNS1 | chr19 | Exonic | 3.6122 | 0.0211 |
| hsa_circ_0017728 | DHTKD1 | chr10 | Exonic | 3.5956 | 0.0211 |
| hsa_circ_0003006 | FLNB | chr3 | Exonic | 2.6322 | 0.0147 |
| hsa_circ_0082600 | TRIM24 | chr7 | exonic | 2.4288 | 0.0217 |
| Upregulated circRNAs | |||||
| hsa_circ_0083815 | INTS9 | chr8 | Exonic | 1.7443 | 0.0119 |
| hsa_circ_0000863 | PRSS57 | chr19 | Sense overlapping | 1.7377 | 0.0131 |
| hsa_circ_0047460 | FHOD3 | chr18 | Exonic | 1.6985 | 0.0157 |
| hsa_circ_0090682 | HUWE1 | chrX | Exonic | 1.6755 | 0.0085 |
| hsa_circ_0049472 | PRKCSH | chr19 | Exonic | 1.6739 | 0.0296 |
| hsa_circ_0028671 | TAOK3 | chr12 | Exonic | 1.6709 | 0.0284 |
| hsa_circ_0000932 | SUPT5H | chr19 | Exonic | 1.5994 | 0.0252 |
| hsa_circ_0001136 | ASXL1 | chr20 | Exonic | 1.5949 | 0.0198 |
| hsa_circ_0085918 | PLEC | chr8 | Exonic | 1.5861 | 0.0318 |
| hsa_circ_0005835 | C16orf62 | chr16 | Exonic | 1.5629 | 0.0443 |