Table 1A.
Patient information for nPOD pancreata samples.
| nPOD ID | Serum AA* | Region | Age† | Sex | BMI | Ethnicity | Cause of Death†† | C-peptide (ng/ml) | Pancreas Weight (g) | RNA RIN |
|---|---|---|---|---|---|---|---|---|---|---|
| Normal Controls | ||||||||||
| 6102 | Negative | body | 45 | F | 35.1 | Caucasian | CVS | 0.55 | 87.32 | 4.6 |
| 6172 | Negative | tail | 19 | F | 32.4 | Caucasian | CVS | 8.02 | 59.7 | 5.8 |
| 6179 | Negative | tail | 21 | F | 20.7 | Caucasian | HT | 2.74 | 72.4 | 5.2 |
| 6227 | Negative | body | 17 | F | 26.4 | Caucasian | CVS | 2.75 | 60.4 | 5.6 |
| 6229 | Negative | body | 31 | F | 26.9 | Caucasian | HT | 6.23 | 45.6 | 7 |
| 6234 | Negative | body | 20 | F | 25.6 | Caucasian | HT | 6.89 | 49.86 | 3.7 |
| 6253 | Negative | body | 19 | F | 34.3 | African American | HT | 7.22 | 102.31 | 5.3 |
| AA+ subjects | ||||||||||
| 6027 | ZnT8A+ | tail | 18 | M | 19.9 | Caucasian | n/a | n/a | 52.9 | 4.4 |
| 6090 | GADA+ | head | 2 | M | 18.8 | Hispanic/Latino | HT | 5.34 | 19.3 | 5.5 |
| 6123 | GADA+ | head | 23 | F | 17.6 | Caucasian | HT | 2.01 | 48.34 | 7.6 |
| 6170 | GADA+ | head | 34 | F | 36.9 | African American | A | 4.29 | 110.3 | 7.6 |
| 6184 | GADA+ | body | 47 | F | 27 | Hispanic/Latino | HT | 3.42 | 71.8 | 4.4 |
| 6197 | GADA+ IA-2A+ | tail | 22 | M | 28.2 | African American | HT | 17.48 | 73.3 | 8.1 |
| Established T1D subjects | ||||||||||
| 6088 | GADA+ IA-2A+ ZnT8A+ mIAA+ | head | 31 (T1D: 5) |
M | 27 | Caucasian | HT | <0.05 | 32 | 5.5 |
| 6143 | IA-2A+ mIAA+ | head | 32 (T1D: 7) |
F | 26.1 | Caucasian | A | <0.05 | 35.7 | 8.5 |
| 6148 | GADA+ mIAA+ | head | 17 (T1D: 7) |
M | 23.9 | Caucasian | A | 0.06 | 26.36 | 5.0 |
| 6161 | IA-2A+ mIAA+ | head | 19 (T1D: 7) |
F | 36.1 | Caucasian | CVS | <0.05 | 39.8 | 5.0 |
| 6180 | GADA+ IA-2A+ ZnT8A+ mIAA+ | body | 27 (T1D: 11) |
M | 25.9 | Caucasian | HT | <0.05 | 36.7 | 4.0 |
| 6241 | mIAA+ | body | 33 (T1D: 31) |
M | 18.4 | Caucasian | CVS | <0.05 | 24.92 | 8.0 |
| 6245 | GADA+ IA-2A+ | body | 22 (T1D: 7) |
M | 23.2 | Caucasian | HT | <0.05 | 31.58 | 7.2 |
| 6258 | mIAA+ | body | 39 (T1D: 37) |
F | 28.7 | Caucasian | HT | <0.05 | 32.56 | 5.4 |
| 6263 | Negative | body | 34 (T1D: 21) |
M | 23.5 | Hispanic/Latino | CVS | 3.18 | 51.59 | 7.8 |
| 6266 | GADA+ IA-2A+ mIAA+ ZnT8A+ | body | 30 (T1D: 23) |
M | 27.1 | Caucasian | A | <0.05 | 51.66 | 6.6 |
*GAD, Glutamic acid decarboxylase; IA2+, Insulinoma-associated protein 2; mIAA+, micro-Insulin auto-antibody; ZnT8, Zinc transporter 8 as determined by nPOD. Methods used for AA+ detection are available at: http://www.jdrfnpod.org/for-investigators/standard-operating-procedures/.
†For T1D samples, years with T1D are indicated.
††Cause of Death: HT, Head trauma; CVS, Cerebrovascular/Stroke; A, Anoxia.