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. 2020 Dec 7;8:601216. doi: 10.3389/fbioe.2020.601216

FIGURE 3.

FIGURE 3

Glucose colorimetric assay prototype for home-testing of saliva samples. (A) Schematics of the assay. The blue color of the membrane (due to the MGNPs on its surface) changes to pink/red if the saliva sample presents hyperglycemic conditions. (B) Colorimetric assay applied to human saliva (ctrl) and to human saliva supplemented with glucose at the concentration of 15 mg/dL (0.8 mM, S1) and 30 mg/dL (1.6 mM, S2). (C) Reflectance spectra of the membrane substrates, related to ctrl and S2 (picture in inset), showing a clear blue-shift (from λ = 600–550 nm). HR-SEM micrographs of (D) ctrl assay (blue) and (E) sample S2 (red) assay (scale bars: 100 nm).