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. 2020 Dec 3;11:600622. doi: 10.3389/fmicb.2020.600622

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Copyright © 2020 Srinivasan, Devi, Santhakumari, Kannappan, Chen, Ravi and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inhibitory effect of NA on the QS controlled virulence factors production. The graph illustrates percentages of biofilm, hemolysin, lipase, and elastase inhibition in A. hydrophila upon treatment with NA at different concentrations (93.75–750 μg/ml). Results indicate the mean values of three independent experiments and SD. The Tukey’s multiple comparisons test (one-way analysis of variance) was used to compare the groups. ^ap ≤ 0.0001 when compare to control, ^bp ≤ 0.0001 when compare to 93.75 μg/ml, and ^cp ≤ 0.0001 when compared to 187.5 μg/ml.