TABLE 1.

Inflammatory mediator levels in the connective tissue of the thoracolumbar region per group.

	Saline		Car		Saline + MFS		Car + MFS		p values
	Median	Q3–Q1	Median	Q3–Q1	Median	Q3–Q1	Median	Q3–Q1
TGF-β1	0.77	0.54	1.85	2.52	1.97	2.95	3.18	3.68	0.048*
TNF	0.63	4.36	0.86	2.44	1.12	2.41	0.92	2.72	0.555
IL-4	0.49	2.07	3.37	6.86	4.8	7.04	7.35	11.38	0.009**
IL-6	0.52	1.84	0.76	11.17	1.16	4.16	0.82	18.24	0.389
MCP-1	51.2	132.6	34.5	234.8	110	208.9	46.6	155.5	0.845
Ly-6G	4.42	7.12	1.23	3.40	3.89	13.61	1.62	3.62	0.437
F4/80	0.88	2.44	0.523	1.63	1.5	4.103	0.343	3.00	0.001**
NOS-2	0.95	8.02	0.3	1.65	1.18	3.612	0.293	0.65	0.002**

Mediator levels on the connective tissues of the thoracolumbar region per group are represented by median and interquartile interval (Q3–Q1). Kruskal–Wallis with Dunn post hoc was used for statistical analysis for all variables. *There was significant (p < 0.05) difference for TGF-β1, IL-4, Ly-6G, and NOS-2. Differences were found between saline vs. Car + MFS (*p = 0.047) for TGF-β1; saline vs. Car + MFS (*p = 0.026) for IL-4; Car vs. saline + MFS (**p = 0.003) and saline + MFS vs. Car + MFS (*p = 0.0337) for Ly-6G; saline vs. Car + MFS (*p = 0.0337) and saline + MFS vs. Car + MFS (*p = 0.0195) for NOS-2.