Table 1.

Dkk3-enriched signal pathway in colorectal cancer according KEGG analysis.

Pathway	Size	P value
Focal adhesion	197	<0.001
Gap junction	87	<0.001
Cytokine -cytokine receptor interaction	234	<0.001
Cell adhesion molecules CAMS	129	<0.001
Dilated cardiomyopathy	86	<0.001
Chemokine signaling pathway	183	<0.001
Hypertrophic cardiomyopathy	79	<0.001
Leukocyte transendothelial migration	111	<0.001
Hedgehog signaling pathway	54	<0.001
Regulation of actin cytoskeleton	207	<0.001
Melanogenesis	99	<0.001
ECM receptor interaction	83	<0.001
Axon guidance	127	<0.001
Pathways in cancer	322	<0.001
Basal cell carcinoma	54	<0.001
Arrhythmogenic right ventricular cardiomyopathy	71	0.001
Complement and coagulation cascades	64	0.001
Neuroactive ligand receptor interaction	231	0.001
JAK-STAT signaling pathway	130	0.001
Leishmania infection	70	0.005
TOLL-like receptor signaling pathway	87	0.006
Glycosaminoglycan biosynthesis chondroitin sulfate	22	0.006
Vascular smooth muscle contraction	113	0.006
Hematopoietic cell lineage	81	0.006
Calcium signaling pathway	169	0.007
TGF-β signaling pathway	85	0.009
MAPK signaling pathway	257	0.015
Glycosaminoglycan biosynthesis heparan sulfate	26	0.02
Melanoma	70	0.039