Table 3.
Participant groups | Multi-way ANOVA | ||||||
---|---|---|---|---|---|---|---|
Frequent users | Infrequent users | Healthy controls | Treatment | Group | Treatment x group | ||
Actual amount of SOL misperception (minutes)a | Placebo | 75.5 ± 82.9 | 33.4 ± 33.2 | 15.2 ± 25.6 |
F = 10.80, p < 0.01 |
F = 6.08, p < 0.01 |
F = 2.49, p = 0.09 |
Zopiclone | 19.5 ± 38.6 | 12.3 ± 13.3 | 5.5 ± 20.6 | ||||
Actual amount of TST misperception (minutes)b | Placebo | 19.4 ± 42.6 | 11.2 ± 50.1 | − 7.1 ± 47.3 |
F = 10.41, p < 0.01 |
F = 6.87, p < 0.01 |
F = 4.05, p = 0.02 |
Zopiclone | 104.4 ± 82.2 | 76.7 ± 113.5 | 3.7 ± 39.8 | ||||
Estimated amount of SOL misperception (minutes)c | Placebo | 18.1 ± 17.6 | 9.1 ± 12.9 | 9.4 ± 13.5 |
F = 16.1, p < 0.001 |
F = 1.70, p = 0.19 |
F = 0.60, p = 0.55 |
Zopiclone | 57.6 ± 72.9 | 47.5 ± 47.8 | 29.2 ± 30.5 | ||||
Prediction error of misperception (minutes)d | Placebo | 18.6 ± 73.1 | − 13.4 ± 61.3 | − 11.3 ± 20.7 |
F = 0.20, p = 0.65 |
F = 1.62, p = 0.20 |
F = 1.01, p = 0.37 |
Zopiclone | 4.7 ± 34.2 | 3.9 ± 20.2 | − 3.1 ± 24.8 |
aThe difference between self-reported subjective SOL obtained from the sleep diary and objective SOL
bThe difference between subjective TST obtained from the sleep diary and objective TST
cThe difference between subjective SOL estimated from the hypnogram and objective SOL
dThe difference between estimated amount of SOL misperception and actual amount of SOL misperception