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. 2020 Sep 17;238(1):83–94. doi: 10.1007/s00213-020-05660-3

Table 3.

Parameters of SOL and TST misperception per group and treatment condition (average ± standard deviation)

Participant groups Multi-way ANOVA
Frequent users Infrequent users Healthy controls Treatment Group Treatment x group
Actual amount of SOL misperception (minutes)a Placebo 75.5 ± 82.9 33.4 ± 33.2 15.2 ± 25.6

F = 10.80,

p < 0.01

F = 6.08,

p < 0.01

F = 2.49,

p = 0.09

Zopiclone 19.5 ± 38.6 12.3 ± 13.3 5.5 ± 20.6
Actual amount of TST misperception (minutes)b Placebo 19.4 ± 42.6 11.2 ± 50.1 − 7.1 ± 47.3

F = 10.41,

p < 0.01

F = 6.87,

p < 0.01

F = 4.05,

p = 0.02

Zopiclone 104.4 ± 82.2 76.7 ± 113.5 3.7 ± 39.8
Estimated amount of SOL misperception (minutes)c Placebo 18.1 ± 17.6 9.1 ± 12.9 9.4 ± 13.5

F = 16.1,

p < 0.001

F = 1.70,

p = 0.19

F = 0.60,

p = 0.55

Zopiclone 57.6 ± 72.9 47.5 ± 47.8 29.2 ± 30.5
Prediction error of misperception (minutes)d Placebo 18.6 ± 73.1 − 13.4 ± 61.3 − 11.3 ± 20.7

F = 0.20,

p = 0.65

F = 1.62,

p = 0.20

F = 1.01,

p = 0.37

Zopiclone 4.7 ± 34.2 3.9 ± 20.2 − 3.1 ± 24.8

aThe difference between self-reported subjective SOL obtained from the sleep diary and objective SOL

bThe difference between subjective TST obtained from the sleep diary and objective TST

cThe difference between subjective SOL estimated from the hypnogram and objective SOL

dThe difference between estimated amount of SOL misperception and actual amount of SOL misperception