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. 2021 Jan 8;11:48. doi: 10.1038/s41598-020-80084-9

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Enrichment of four functional annotations among loci jointly associated with birth weight and childhood obesity traits. (A) European birth weight and childhood body mass index (BW_EU-CBMI), (B) European birth weight and childhood obesity (BW_EU-COB), (C) Trans-ethnic birth weight and childhood body mass index (BW_TR-CBMI), (D) Trans-ethnic birth weight and childhood obesity (BW_TR-COB). The bars denote the enrichment fold for variants that are associated jointly with BW and childhood obesity traits (red), only with birth weight (green), and only with childhood obesity traits (blue), respectively.