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. 2021 Jan 8;11:248. doi: 10.1038/s41598-020-80093-8

Figure 1.

Figure 1

Plasma microbial-derived metabolites distinguish alcohol-exposed and control dams. (a) Dimension 1 and 2 of the PCA on the scaled metabolite profiles within plasma of nine control (CON) and eight alcohol-exposed (ALC) dams. (b) PCA biplot with microbial-derived metabolites overlaid onto the samples plot. PCA values for the MDPs are presented in Supplemental Table S2. (c) T-statistic plot of all 813 metabolites (arranged alphabetically along the x-axis) against their log10 q-values. The black dashed line indicates the cut-off for the FDR adjusted value of q < 0.05, and the red dashed line indicates q < 0.01. Red dots indicate microbial-derived metabolites having q < 0.05. Sample size is n = 9 control and n = 8 alcohol-exposed dams.