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. 2021 Jan 8;11:12. doi: 10.1038/s41598-020-79586-3

Figure 2.

Figure 2

Interleukin 6 CSF levels in cases with no DCI, with DCI and no infarction, and in patients with DCI and infarction. (a) In all three patient groups a significant increase of CSF IL-6 levels was seen in the first week after SAH with a peak on day 5 (day 1 vs. day 5; no DCI P = 0.039, DCI w/o infarction P = 0.003, DCI with infarction P < 0.001). (b) Boxplots show the inter-group comparison for days 2, 5 and 14. While median CSF IL-6 levels did not differ significantly on day 2 (DCI with infarction vs. no DCI and ~ vs. DCI w/o infarction: P = 0.61 and P = 0.55), there were significant differences between median CSF IL-6 levels in the DCI with infarction group and both other groups (no DCI and DCI w/o infarction: P < 0.0001 and P = 0.0024) on day 5. This effect persists for several days (not shown) and is no longer seen on day 14 (DCI with infarction vs. no DCI and ~ vs. DCI w/o infarction: P = 0.83 and P = 0.20).