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Biocompatibility and safety of fCNC (A) in vitro and (B) in vivo. There was no evidence of human kidney epithelial cell toxicity arising from treatment with fCNC in vitro. Cell viability did not decrease across a range of fCNC doses. The fCNC was biocompatible and safe in naïve mice as indicated by absence of weight loss upon treatment. There was no signs of lethargy or absence of grooming noted in these animals.
