Table 1.
Disease characteristics of the bottom, middle (47.5 to 52.5 percentiles), and top 5% of the DRS, DRSA, and PRS distributions in the validation set for each three skin cancer.
| BCC | SCC | Melanoma | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Bottom | Middle | Top | Bottom | Middle | Top | Bottom | Middle | Top | |
| DRS | |||||||||
| At baseline: | |||||||||
| No. of cases | 14 | 604 | 2593 | 19 | 275 | 1608 | 14 | 116 | 916 |
| Sex (% of females) | 85.7 | 66.2 | 48.5 | 78.9 | 65.1 | 45.1 | 78.6 | 66.4 | 46.1 |
| Age | 40.4 (7.2) | 60.7 (9.8) | 72.0 (8.8) | 36.1 (6.4) | 60.0 (8.3) | 73.3 (8.5) | 40.4 (8.3) | 62.2 (10.8) | 66.2 (10.3) |
| Age of diagnosis | 33.7 (8.8) | 49.0 (12.1) | 51.4 (14.5) | 26.7 (6.6) | 51.1 (11.5) | 56.8 (13.7) | 26.9 (9.2) | 51.5 (14.1) | 51.9 (13.9) |
| Cancer stage at diagnosis | 0.00 (0.00) | 1.06 (0.24) | 1.24 (0.51) | 0.00 (0.00) | 1.08 (0.28) | 1.27 (0.53) | 0.00 (0.00) | 1.33 (0.58) | 1.33 (0.53) |
| No. cancer diagnosed in the last two years | 1.36 (0.50) | 1.57 (0.66) | 1.97 (0.89) | 1.26 (0.56) | 1.56 (0.60) | 1.83 (0.81) | 1.21 (0.43) | 1.41 (0.64) | 1.36 (0.60) |
| No. of different type of skin cancer | 1.07 (0.27) | 1.22 (0.45) | 1.69 (0.67) | 1.05 (0.23) | 1.47 (0.56) | 2.00 (0.62) | 1.07 (0.27) | 1.41 (0.68) | 1.84 (0.83) |
| Incident cases: | |||||||||
| No. of incident cases | <5 | 57 | 123 | <5 | 34 | 113 | <5 | 18 | 36 |
| Sex (% of females) | na | 66.7 | 44.7 | na | 64.7 | 35.4 | na | 72.2 | 44.4 |
| Age | na | 61.6 (9.1) | 71.8 (8.7) | na | 59.0 (7.2) | 73.6 (7.8) | na | 59.1 (10.2) | 67.5 (10.8) |
| % of incident cases | na | 2.62 | 11.98 | na | 1.46 | 7.13 | na | 0.73 | 1.72 |
| Cancer free: | |||||||||
| No. of cancer free | 5 | 277 | 928 | 6 | 139 | 614 | 8 | 54 | 463 |
| Sex (% of females) | 50 | 66.7 | 44.7 | 100 | 64.7 | 35.4 | 100 | 72.2 | 44.4 |
| Age | 44.5 (19.1) | 61.6 (9.1) | 71.8 (8.7) | 41.0 (0.0) | 59.0 (7.2) | 73.6 (7.8) | 36.0 (0.0) | 59.1 (10.2) | 67.5 (10.8) |
| % of cancer free | 100 | 84.7 | 59.6 | 100 | 86.9 | 64.5 | 100 | 91.5 | 90.1 |
| DRSA | |||||||||
| At baseline: | |||||||||
| No. of cases | 208 | 715 | 2125 | 100 | 299 | 1160 | 63 | 148 | 906 |
| Sex (% of females) | 69.2 | 59.3 | 58 | 71 | 53.5 | 53.3 | 77.8 | 45.3 | 51.5 |
| Age | 71.4 (8.9) | 66.9 (10.2) | 61.6 (10.9) | 68.2 (11.2) | 69.4 (9.7) | 63.9 (10.0) | 69.0 (9.0) | 66.7 (10.9) | 58.5 (13.2) |
| Age of diagnosis | 59.0 (13.4) | 53.6 (13.0) | 44.5 (12.7) | 58.9 (13.5) | 57.7 (12.1) | 49.2 (12.4) | 54.3 (13.7) | 52.0 (14.6) | 45.3 (14.8) |
| Cancer stage at diagnosis | 1.20 (0.42) | 1.20 (0.48) | 1.23 (0.51) | 1.00 (0.00) | 1.29 (0.61) | 1.26 (0.57) | 1.50 (0.71) | 1.14 (0.38) | 1.32 (0.54) |
| No. cancer diagnosed in the last two years | 1.41 (0.55) | 1.66 (0.72) | 1.91 (0.84) | 1.43 (0.63) | 1.68 (0.71) | 1.79 (0.77) | 1.20 (0.45) | 1.34 (0.62) | 1.36 (0.58) |
| No. of different type of skin cancer | 1.14 (0.35) | 1.30 (0.51) | 1.63 (0.66) | 1.35 (0.52) | 1.62 (0.58) | 1.98 (0.62) | 1.35 (0.60) | 1.54 (0.72) | 1.70 (0.80) |
| Incident cases: | |||||||||
| No. of incident cases | 21 | 47 | 97 | 8 | 26 | 91 | <5 | 11 | 28 |
| Sex (% of females) | 71.4 | 55.3 | 53.6 | 62.5 | 61.5 | 46.2 | na | 45.5 | 57.1 |
| Age | 71.2 (10.6) | 65.5 (9.0) | 60.2 (10.6) | 68.0 (10.8) | 68.8 (10.5) | 63.3 (10.1) | na | 62.3 (14.5) | 59.6 (12.0) |
| % of incident cases | 0.91 | 2.35 | 7.78 | 0.34 | 1.16 | 5.03 | na | 0.48 | 1.4 |
| Cancer free: | |||||||||
| No. of cancer free | 102 | 285 | 811 | 50 | 124 | 466 | 32 | 85 | 439 |
| Sex (% of females) | 71.4 | 55.3 | 53.6 | 62.5 | 61.5 | 46.2 | 100 | 45.5 | 57.1 |
| Age | 71.2 (10.6) | 65.5 (9.0) | 60.2 (10.6) | 68.0 (10.8) | 68.8 (10.5) | 63.3 (10.1) | 72.0 (0.0) | 62.3 (14.5) | 59.6 (12.0) |
| % of cancer free | 82.3 | 75.2 | 64.2 | 92.6 | 75.2 | 66.3 | 100 | 95.5 | 90.7 |
| PRS | |||||||||
| At baseline: | |||||||||
| No. of cases | 336 | 747 | 1559 | 182 | 398 | 776 | 123 | 215 | 392 |
| Sex (% of females) | 60.1 | 56.5 | 57.4 | 59.9 | 58.8 | 55.8 | 54.5 | 53 | 55.4 |
| Age | 67.6 (10.6) | 66.4 (10.2) | 64.4 (10.8) | 66.4 (10.1) | 67.9 (10.7) | 66.1 (9.3) | 63.1 (11.0) | 63.2 (12.1) | 62.5 (13.2) |
| Age of diagnosis | 54.0 (14.2) | 53.0 (12.9) | 48.2 (13.2) | 55.7 (13.2) | 56.3 (12.8) | 53.2 (12.4) | 51.6 (15.4) | 49.7 (14.8) | 49.1 (15.7) |
| Cancer stage at diagnosis | 1.11 (0.32) | 1.22 (0.42) | 1.24 (0.52) | 1.00 (0.00) | 1.17 (0.38) | 1.27 (0.62) | 1.33 (0.52) | 1.25 (0.45) | 1.23 (0.43) |
| No. cancer diagnosed in the last two years | 1.58 (0.70) | 1.66 (0.71) | 1.88 (0.84) | 1.44 (0.62) | 1.66 (0.74) | 1.78 (0.81) | 1.44 (0.68) | 1.39 (0.57) | 1.35 (0.61) |
| No. of different type of skin cancer | 1.30 (0.54) | 1.35 (0.55) | 1.50 (0.61) | 1.48 (0.63) | 1.74 (0.63) | 1.83 (0.62) | 1.41 (0.68) | 1.65 (0.78) | 1.76 (0.80) |
| Incident cases: | |||||||||
| No. of incident cases | 31 | 60 | 78 | 25 | 45 | 73 | 6 | 8 | 32 |
| Sex (% of females) | 51.6 | 50 | 56.4 | 56 | 46.7 | 54.8 | 66.7 | 37.5 | 46.9 |
| Age | 66.4 (12.5) | 65.2 (10.9) | 62.0 (11.2) | 66.4 (10.3) | 67.0 (10.2) | 66.1 (9.9) | 63.7 (12.8) | 65.4 (12.2) | 64.6 (13.2) |
| % of incident cases | 1.4 | 2.9 | 5 | 1.1 | 2 | 3.6 | 0.3 | 0.3 | 1.4 |
| Cancer free: | |||||||||
| No. of cancer free | 149 | 324 | 571 | 77 | 180 | 314 | 57 | 105 | 185 |
| Sex (% of females) | 51.6 | 50 | 56.4 | 56 | 46.7 | 54.8 | 66.7 | 37.5 | 46.9 |
| Age | 66.4 (12.5) | 65.2 (10.9) | 62.0 (11.2) | 66.4 (10.3) | 67.0 (10.2) | 66.1 (9.9) | 63.7 (12.8) | 65.4 (12.2) | 64.6 (13.2) |
| % of cancer free | 78.8 | 75.3 | 62.9 | 88.5 | 73.8 | 68.4 | 89.1 | 89 | 86.4 |
Mean and SD (within parenthesis) are shown for the disease characteristics. Statistics for categories with counts <5 are masked (na) to avoid risk of participant re-identification.
No. number.