Table 1.
Demographics and lung functions derived from the PFTs and QCTs of COPD and non-COPD subjects.
| Non-COPD subjects (n = 392) |
COPD subjects (n = 204) |
P value | |
|---|---|---|---|
| Demographics | |||
| Male/females, n (%) | 190/202 (48.5%/51.5%) | 173/31 (84.8%/15.2%) | < 0.001 |
| Age, years | 55.9 (16.3) | 72.9 (7.4) | < 0.001 |
| Height, cm | 161.3 (10.2) | 161.3 (7.5) | 0.992 |
| Weight, kg | 63.2 (12.0) | 59.8 (9.8) | < 0.001 |
|
Never/former/current smokers, n (%) |
262/54/76 (66.8%/13.8%/19.4%) |
50/53/101 (24.5%/26.0%/49.5%) |
< 0.001 |
|
COPD stages (I, II, III, IV), n (%) |
0 |
88/87/27/2 (43.1%/42.7%/13.2%/1.0%) |
|
| PFT-based lung functions | |||
| FEV1, %predicted | 100.0 (14.1) | 75.0(20.0) | < 0.001 |
| FVC, %predicted | 98.2 (13.6) | 93.1(20.0) | < 0.001 |
| FEV1/FVC × 100 | 80.4 (6.0) | 58.9 (8.0) | < 0.001 |
| QCT-based lung functions | |||
| TLC, litre | 4.7 (1.3) | 4.3 (1.0) | < 0.001 |
| FRC, litre | 3.0 (1.0) | 2.8 (0.9) | 0.005 |
| Emph% | 1.7 (2.5) | 8.5 (7.5) | < 0.001 |
| fSAD% | 11.2 (13.4) | 23.7 (13.6) | < 0.001 |
| ADI | 0.4 (0.1) | 0.3 (0.1) | 0.074 |
| SRI | 0.5 (0.03) | 0.6 (0.03) | < 0.001 |
| J | 1.7 (0.4) | 1.5 (0.3) | < 0.001 |
Values are presented as mean (SD).
QCT, quantitative computed tomography; PFT, pulmonary function test; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s; FRC, functional residual volume; TLC, total lung capacity; Emph%, percent emphysema; fSAD%, percent functional small-airway disease; ADI, anisotropic deformation index; SRI, slab rod index; J, Jacobian.