Figure 4.
(A) Schema of the ketone metabolic pathway. (B) Comparison of mRNA expression levels of ketone metabolizing enzymes or ketone body transport proteins. (*p < 0.05, **p < 0.01, and Tukey–Kramer test). (C) Immunostaining of ketone metabolizing enzymes (OXCT1, BDH1, and ACAT1) and ketone body transport protein (MCT1). Immunostaining analyses analyze 5 tumors in each group. An intensity of immunostainings is quantified using image J software.