Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 8;11:221. doi: 10.1038/s41598-020-80345-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Percentage of tumors that displayed ZNF154 hypermethylation at the probe cg21790626 versus percentage of tumors that displayed mutations in a set of cancer-associated genes for the given cancer type. The percent tumors with a mutation in a cancer gene set on the x-axis are the fraction of tumors that have a mutation in any of the cancer genes of the associated cancer gene set. Methylation data were obtained from The Cancer Genome Atlas and mutation data were obtained from cBioPortal. *A cancer-associated gene was included in a set if it was listed in the OncoKB database and expected to be recurrently mutated in > 10% of samples for a given tumor type, based on cBioPortal mutation frequencies. Lists of cancer associated genes for each cancer type are located in Table 3. BLCA bladder urothelial carcinoma (n = 130), BRCA breast invasive carcinoma (n = 664), HNSC head and neck squamous cell carcinoma (n = 510), KIRC kidney renal clear cell carcinoma (n = 263), KIRP kidney renal papillary cell carcinoma (n = 267), LIHC liver hepatocellular carcinoma (n = 373), LUAD lung adenocarcinoma (n = 185), OV ovarian carcinoma (n = 302), PAAD pancreatic adenocarcinoma (n = 150), PRAD prostate adenocarcinoma (n = 498), STAD stomach adenocarcinoma (n = 349).