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. 2021 Jan 8;11:221. doi: 10.1038/s41598-020-80345-7

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021

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ZNF154 methylation in stage I solid tumors. The probe cg21790626 was measured in 10 types of stage I solid tumor (red) or healthy tissue samples (blue), in Illumina 450 K methylation microarray data provided by TCGA or Bartlett et al. (Serous_EOC¹⁵, n = 7, and fallopian tube controls¹⁶, n = 216). Significant hypermethylation was found for all tumor types except for LUAD and STAD. “ns” not significant; *p < 0.05; **p < 0.01; ***p < 0.001; p values derived from Wilcoxon rank sum two-sided tests. Data plotted as standard box plot and whiskers. BLCA bladder urothelial carcinoma, BRCA breast invasive carcinoma, HNSC head and neck squamous cell carcinoma, KIRC kidney renal clear cell carcinoma, KIRP kidney renal papillary cell carcinoma, LIHC liver hepatocellular carcinoma, LUAD lung adenocarcinoma, PAAD pancreatic adenocarcinoma, STAD stomach adenocarcinoma, Serous_EOC serous subtype epithelial ovarian carcinoma.