Table 4.

Optimal cutoffs of normalized methylated ZNF154 cfDNA fragments per mL plasma and the resulting classification AUCs, and optimal true positive rate (TPR) and false positive rate (FPR) for each plasma sample set.

Sample set	Cutoff (normalized fragments/mL plasma)	AUC	TPR	FPR	Sample size (tumor/normal)
Late stage pancreatic cancer	14.69	0.85	0.94	0.20	17/20
Early stage pancreatic cancer	15.96	0.87	1.00	0.20	8/20
Ovarian cancer	13.81	0.85	0.87	0.20	38/20
Liver cancer	21.89	0.48	0.50	0.10	4/20
Colon cancer	29.83	0.75	0.75	0.00	4/20