Table 3.
The hematological and biochemical parameters in the effects of 5 Gy gamma radiation on 1, 3, 7, 14, 21, and 30 days post-irradiation.
| Indexes | Control group | 5 Gy gamma-radiation group | |||||
|---|---|---|---|---|---|---|---|
| 1 day | 3 day | 7 day | 14 day | 21 day | 30 day | ||
| Body Weight (g) | 21.5 ± 2 | 19.7 ± 2.8 | *18.8 ± 2.4 | 19.8 ± 2.7 | 20.6 ± 2.2 | 21.6 ± 2.4 | 23 ± 2.1 |
| WBC (1000/mm3) | 6.8 ± 1.7 | *2.2 ± 0.4 | *0.98 ± 0.2 | *1.23 ± 0.5 | *2.9 ± 0.5 | 6.5 ± 2.5 | 8.9 ± 2.9 |
| RBC (Millin/mm3) | 9.3 ± 1.8 | 9.2 ± 2.1 | 8.5 ± 2.6 | 8.2 ± 2.5 | 8.4 ± 2.7 | 8.8 ± 2.2 | 9.3 ± 2.9 |
| Lymphocytes (%) | 72.8 ± 5.3 | *22 ± 13 | *22.5 ± 8 | *28.2 ± 3.2 | *46 ± 9 | 65 ± 12 | 84 ± 8 |
| Neutrophils (%) | 21 ± 3.2 | *75.2 ± 15 | *77.5 ± 1.9 | *62.1 ± 2.8 | 52 ± 3.7 | 33 ± 2.3 | 11 ± 2.9 |
| Monocytes (%) | 6.1 ± 1.7 | 2.1 ± 0.6 | 2.7 ± 0.9 | 6.3 ± 1.8 | 5.7 ± 1.5 | 6.6 ± 1.7 | 6.4 ± 1.4 |
| HCT (%) | 40.8 ± 2.5 | 38 ± 2.4 | 36.6 ± 3.7 | 38.3 ± 2.5 | 38.5 ± 2.8 | 43 ± 3.6 | 41 ± 3.9 |
| PLT (1000/mm3) | 1172 ± 115 | 1041 ± 131 | 934 ± 144 | 890 ± 145 | 1136 ± 260 | 954 ± 126 | 1111 ± 210 |
| ALT (U/L) | 1288 ± 125 | 1345 ± 123 | *1543 ± 200 | 885 ± 233 | 853 ± 156 | 888 ± 132 | 1109 ± 164 |
| AST (U/L) | 117 ± 15 | 125 ± 25 | *148 ± 28 | *142 ± 23 | 126 ± 33 | 120 ± 29 | 125 ± 33 |
| ALP (U/L) | 284 ± 34 | 255 ± 52 | *455 ± 44 | *434 ± 32 | 333 ± 64 | 312 ± 65 | 295 ± 52 |
| BUN (mg/dL) | 64 ± 10 | 75 ± 15 | 70 ± 18 | 66 ± 15 | 60 ± 12 | 65 ± 14 | 65 ± 17 |
| Cr (mg/dL) | 0.4 ± 0.05 | 0.7 ± 0.09 | 0.4 ± 0.05 | 0.5 ± 0.07 | 0.4 ± 0.08 | 0.4 ± 0.06 | 0.4 ± 0.08 |
| T.P (mg/dL) | 5.8 ± 1.2 | 6.3 ± 1.5 | 5.2 ± 1.5 | 5 ± 1.5 | 4.9 ± 2 | 5 ± 1.5 | 5.4 ± 2.5 |
| Glu (mg/dL) | 195 ± 25 | 210 ± 33 | 225 ± 44 | 234 ± 50 | 220 ± 55 | 235 ± 48 | 240 ± 65 |
| B.T (mg/dL) | 0.9 ± 0.2 | 1.2 ± 0.2 | 0.75 ± 0.3 | 0.7 ± 0.3 | 0.85 ± 0.2 | 0.85 ± 0.3 | 0.9 ± 0.4 |
| B.Direct (mg/dL) | 0.39 ± 0.1 | 0.5 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.5 ± 0.2 | 0.55 ± 0.3 | 0.4 ± 0.1 |
| Alb (mg/dL) | 2.9 ± 0.6 | 3.1 ± 1 | 2.4 ± 1 | 3 ± 1 | 2.5 ± 0.8 | 3.3 ± 0.5 | 3.5 ± 0.9 |
Values are means ± SD. *P < 0.05 compared to the control group. Values are means ± SD. RBC = red blood cell, HCT = hematocrit, WBC = white blood cells, Plt = platelets, BUN = blood urea nitrogen, Cr = creatinine, Glu = glucose, AST = aspartate transaminase, ALT = alanine transaminase, ALP = alkaline phosphatase, Alb = albumin, T.P = total protein, B.T = Bilirubin Total, B.Direct = Bilirubin Direct.